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Amazon.com has the Logitech Harmony 1000 Advanced Universal Remote for $249.99 with free shipping.
Final Price for this deal: $249.99 + Free Shipping

Description:
* Simply touch one icon and the Harmony remote will power on all the necessary components
* Large, color icons and backlit buttons ensure an entirely new level of ease and functionality
* Simply connect the Harmony 1000 to your computer, and the wizard guides you through the entire set-up process
* No need to worry about power with the rechargeable Lithium-ion battery. The handy recharging stand ensures that the unit is always powered up and easy to find
* Control everything from HDTVs to PVR/DVRs, from laser discs to VCRs, even lighting controls! Logitech's online database now includes 4500+ brands and 150,000+ IR devices